XL-888: Uses, Interactions, Mechanism of Action - DrugBank

XL888 LOGIN oleh O Alese · 2024 — We developed a phase Ib trial to evaluate the safety, immunogenicity and preliminary antitumor activity of Pembro and XL888 in patients with advanced CRC. XL888 is a heat shock protein-90 (HSP90) inhibitor, with an IC50 of 24 nM. For research use only. We do not sell to patients. XL888 Chemical Structure. XL-888 is a novel and orally-bioavailable inhibitor of heat shock protein 90 (HSP90) that selectively inhibits HSP90α and HSP90β with IC50s of 22 nM and 44 nM - Link Alternatif Terbaru